CH2O1: Further Organic Chemistry

Module Provider:

School of Chemistry

Number of credits:

20 [10 ECTS credits]

Level:

I (Intermediate)

Terms in which taught:

Spring and Summer

Module Convenor:

Prof LM Harwood

Pre-requisites:

CH1O1

Co-requisites:

Modules excluded:

CH2O2

Current from:

2005/6

Aims:
To build on the basic concepts of organic chemistry with a more detailed treatment of selected topics.

Assessable learning outcomes:
Students who have successfully completed this module will be able to:

Additional outcomes:
Students should develop more advanced skills in the techniques of practical organic chemistry and in addition demonstrate the ability to word process reports for laboratory classes, further enhancing their computing skills. The tutorial/workshop environment will improve the students' oral and presentation skills.

Outline content:
P Comina (5 lectures) Carbonyl Chemistry (II)
Revision of a-acidity of carbonyl compounds. The aldol condensation reaction, crossed aldol condensations, Claisen condensation, Dieckmann condensation, the use of 1,3-dicarbonyl compounds, decarboxylation of 1,3-keto-acids, Michael addition reactions, Robinson annelation.
L M Harwood (10 lectures) Heterocyclic Chemistry
Synthesis and reactions of pyrroles, furans, thiophenes, indoles, pyridines, quinolines and isoquinolines.
L M Harwood (5 lectures) Molecular Rearrangements
Topics covered will include the Beckmann, pinacol, Curtius, Hofmann, Baeyer-Villiger and Lossen rearrangements and their use for the synthesis of molecules of industrial importance.
H M I Osborn (10 lectures) Alicyclic Chemistry
This course will provide conformational analysis for cyclic compounds, and also for their non-cyclic counterparts. Factors affecting the ease of cyclisation of substrates to afford small, normal and large rings, will also be discussed, with examples.
J B Sweeney (5 lectures) Organometallics
Methods for forming C-C bonds using organometallic reagents; basic aspects of preparative carbanion chemistry.
M G B Drew (7 hours) IT Skills
The course will consist of four sections in which students use different software packages including databases, spreadsheets, molecular modelling, and word processing. Students will gain hands-on experience in all the different types of software and carry out a systematic survey via a series of set problems relevant to chemistry.

Brief description of teaching and learning methods:
Approximately three one-hour lectures per week with roughly one tutorial or workshop on related material every two weeks. Students attend five eight-hour practical sessions over the duration of the module. In Term 3 students attend a pre-practical course on IT skills which is a pre-requisite for practical work throughout the remainder of the course.

Contact hours:

Assessment:
Coursework
Students attend tutorials and workshops on the material covered in this module. Attendance is compulsory at both. Both tutorial work and workshop problems form the basis of the open-book examination held at the end of the spring term. Practical work is assessed both through work in the laboratory and the resultant reports. The IT course is assessed by a written report and set problems. Tutorials and practical reports must be submitted by the named date.
Relative percentage of coursework: Practical work 25%; IT skills 5%.
Examinations
One two-hour written paper during the Part 2 examination period. 50%
One one-hour open book examination based on tutorial and workshop material at the end of the spring term 20%
Requirements for a pass in this module
A mark of 40% overall.
Reassessment arrangements
Re-examination in September for the examined component.