CH2O2: Organic Chemistry for Biochemists

Module Provider:

School of Chemistry

Number of credits:

10 [5 ECTS credits]

Level:

I (Intermediate)

Terms in which taught:

Spring

Module Convenor:

Dr JE McKendrick

Pre-requisites:

CH1O1

Co-requisites:

Modules excluded:

CH2O1

Module version for:

2006/7

Aims:
To build on the basic concepts of organic chemistry with an in-depth treatment of selected topics.

Assessable learning outcomes:
Students who have successfully completed this module will be able to:

Additional outcomes:
The tutorial/workshop environment will improve the students' oral and presentation skills.

Outline content:
J E McKendrick (5 lectures) Carbonyl Chemistry (II)
Revision of a-acidity of carbonyl compounds. The Aldol condensation reaction, Crossed Aldol condensations, Claisen condensation, Dieckmann condensation, the use of 1,3-dicarbonyl compounds, decarboxylation of 1,3-keto-acids, Michael addition reactions, Robinson annelation.
L M Harwood (10 lectures) Heterocyclic Chemistry
Synthesis and reactions of pyrroles, furans, thiophenes, indoles, pyridines, quinolines and isoquinolines.
L M Harwood (5 lectures) Molecular Rearrangements
Topics covered will include the Beckmann, pinacol, Curtius, Hofmann, Baeyer-Villiger and Lossen rearrangements and their use for the synthesis of molecules of industrial importance.

Brief description of teaching and learning methods:
Two one-hour lectures per week with approximately three tutorials and three workshops on related material.

Contact hours:

Assessment:
Coursework
Students attend tutorials and workshops on the material covered in this module. Attendance is compulsory at both. Both tutorial work and workshop problems form the basis of the open-book examination held at the end of the spring term.
Relative percentage of coursework: 0%
Examinations
One one-hour written paper during the Part 2 examination period. 80%
One one-hour open book examination based on tutorial and workshop material at the end of the spring term 20%
Requirements for a pass in this module
A mark of 40% overall.
Reassessment arrangements
Re-examination in September for the examined component.