CH2A3: Analytical Chemistry

Module Provider:

Chemistry, School of Chem, FoodBi and Pharm

Number of credits:

20 [10 ECTS credits]

Level:

I (Intermediate)

Terms in which taught:

Autumn and Spring

Module Convenor:

Dr MJ Almond

Pre-requisites:

CH1I1 CH1O1 CH1P1

Co-requisites:

Modules excluded:

CH2A1 CH2A2 PM2DS2

Module version for:

2007/8

Aims:
The aim of this module is to introduce students to a wide range of analytical techniques.

Assessable learning outcomes:
Students should be able to:

Additional outcomes:
The students should improve their team-working skills through practicals, numeracy through problem solving, and oral and presentation skills through tutorials.

Outline content:
M J Almond (2 lectures + 1 workshop) Introduction to Analytical Methods
Choice of analytical methods, methods of sampling; qualitative and quantitative analysis; precision and accuracy, standard deviation.
M J Almond (5 lectures + 1 workshop) UV, AA and IR Spectroscopy
Introduction to spectroscopic methods. Design of the UV-visible spectrometer; quantitative analysis using UV-visible spectroscopy - the Beer-Lambert law. Atomic absorption spectroscopy for the determination of elemental composition. Fourier transform and dispersive infrared spectrometers. Use of infrared spectroscopy for functional group analysis in organic and inorganic chemistry. Introduction to concepts of symmetry using CO2 and SO2 as examples. Introduction to use of isotopic substitution in infrared spectroscopy.
W C Hayes (6 lectures + 1 tutorial) Mass Spectrometry and Chromatographic Techniques
Introduction to mass spectrometry. EI techniques, precise molecular weights, metastable peaks, fragmentation and rearrangements. Principles and applications of gas-liquid chromatography and high performance liquid chromatography.
G Brown (4 lectures + 1 workshop) Nuclear Magnetic Resonance Spectroscopy
Theory and practice of NMR. Spectrometer design for a CW-NMR instrument. Origins and interpretation of chemical shift and peak splitting in 1H NMR spectra (including second order effects and the magnitude of coupling constants). Chemical shift in 13C NMR. Interpretation of 1H NMR spectra from molecules of known and unknown structure.
S J Hibble (3 lectures + 1 workshop) Thermal Methods
Thermogravimetric analysis (TGA) and differential thermogravimetry (DTG) and differential thermal analysis (DTA) and applications of the methods.
S Black (2 lectures) X-ray Methods
X-ray fluorescence and power diffraction as applied to chemical and mineralogical analysis.
W C Hayes, G D Brown and S J Hibble (40 hours) Practical Analytical Chemistry

Brief description of teaching and learning methods:
Approximately two one-hour lectures per week with roughly one tutorial or workshop on related material every two weeks. Students attend five eight-hour practical sessions over the duration of the module.

Contact hours:

Assessment:
Coursework
Students attend tutorials and workshops on the material covered in this module. Attendance is compulsory at both. Lectures, tutorial work and workshop problems form the basis of the open-book examination held at the end of the autumn term. Practical work is assessed both through work in the laboratory and the resultant reports. Tutorials and practical reports must be submitted by the named date.
Relative percentage of coursework: Practical work 25%
Penalties for late submission
In accordance with University policy 10% of the total marks available will be deducted from practical work which is submitted up to 1 week late. Work submitted later than this will receive no credit unless there are extenuating circumstances.
Examinations
One two-hour written paper during the Part 2 examination period. 55%
One one-hour open book examination based on lecture, tutorial and workshop material at the end of the autumn term 20%
Requirements for a pass in this module
A mark of 40% overall.
Reassessment arrangements
Re-examination in September for the examined component.