PM2TH1: Therapeutics 1

Module Provider:

Pharmacy, School of Chem, FoodBi and Pharm

Number of credits:

15 [7.5 ECTS credits]

Level:

I (Intermediate)

Terms in which taught:

Spring

Module Convenor:

Professor G Brooks

Pre-requisites:

Co-requisites:

Modules excluded:

Module version for:

2007/8

Aims:
(1) To introduce the concepts and principles related to the study of human diseases in the cardiovascular and respiratory and renal systems; (2) to present an overview the major diseases that affect the human circulatory, respiratory and renal systems; and (3) to describe current and future treatments of such diseases.

Assessable learning outcomes:
At the end of the Module the student will be expected to:
• Discuss the concepts and principles of studying cardiovascular, respiratory and renal disease processes in humans
• Describe the causes, aetiology, epidemiology and diagnosis of the most important cardiovascular, respiratory and renal diseases affecting humans
• Describe the treatment and management of patients who suffer from such diseases
Give detailed relevant examples of each disease process along with its treatment.

Additional outcomes:
Through additional reading the student will gain computer-aided learning skills via literature database searching.
Practical classes will give students skills in the study of the cardiorespiratory and renal systems
Problem-based learning will provide a structured framework for group work, communication skills and the development of self-learning skills for lifelong learning.

Outline content:
This module introduces the concepts and general principles relating to the study of cardiovascular and respiratory diseases in humans. The course will cover the causes, aetiology, epidemiology, diagnosis and treatment of:
a) coronary and circulatory diseases such as: atherosclerosis, heart failure, stroke, myocardial infarction, arrhythmias, and hypertension.
b) asthma, emphysema, chronic obstructive pulmonary disease (COPD), pneumonia, tuberculosis and cystic fibrosis.
c) The renal and urinary system : Acute and chronic renal failure. Renal stimulation. Replacement therapy and effect on drugs. Diabetes insipidus. Renin, aldosterone, and angiotensin blockade, ACE inhibitors, natriopeptides, diuretics and antidiuretics. Markers of renal function and impact on drug therapy. Bladder function and control. Acid-base and electrolyte control (combined with liver section).

Brief description of teaching and learning methods:
The course content will be provided through a mixture of formal one-hour lectures, problem-based learning seminars using appropriate case studies and practical laboratory classes. Appropriate supplementary information and reading lists will be provided and facilities for computer-aided literature searching for additional relevant materials will enable students to improve their own learning skills.

Contact hours:

Assessment:
Coursework:
Practical Class assessments will contribute 30% and PBL assessments will each contribute 15% to the final assessment

Relative percentage of coursework : 45%

Penalties for late submission: In accordance with University policy

Examinations:
Three one-hour written examinations requiring the answer of three questions out of five. These contribute 55% of the overall assessment for this module.

Requirements for a pass: A mark of 50% overall

Reassessment arrangements: Re-examination (written paper) in September only