Module Provider: |
Pharmacy, School of Chem, FoodBi and Pharm |
Number of credits: |
20 [10 ECTS credits] |
Level: |
H (Honours) |
Terms in which taught: |
Autumn and Spring |
Module Convenor: |
Dr
F
Greco |
Pre-requisites: |
PM1MP1 PM2MP2
|
Co-requisites: |
|
Modules excluded: |
|
Module version for: |
2007/8 |
Aims:
This module aims to develop an understanding of the design and mechanism of action of sophisticated dosage forms. |
Assessable learning outcomes:
Students will be able to:
Understand the concept of bioavailability and how drug properties and biological factors affect bioavailability.
Discuss the issues related to different administration routes and describe the relevant dosage forms
Correlate differences in bioavailability with the administration route used
Define the main pharmacokinetics parameters and apply them to practical cases.
Critically discuss issues related to time-specific, site-specific and targeted drug delivery
Test modified-release dosage forms as outlined in the British Pharmacopoeia
Display a knowledge of the challenges encountered in delivery of macromolecules and show an appreciation for the different strategies used.
Independently retrieve relevant information from the scientific literature and critically assess and summarise the content. |
Additional outcomes:
The students will be introduced to the latest development in the field of drug delivery. By analysing different scientific articles, the students will develop critical skills. In addition, important transferable skills such as communication skills, critical thinking and team working will be improved during workshops. |
Outline content:
1) Biopharmaceutical principles of drug delivery
2) Administration Routes
3) Advanced Pharmacokinetics and their Clinical Applications
4) Time-specific, site-specific and targeted drug delivery.
5) Challenges in formulation and delivery of macromolecules
Reading List
Aulton M. Pharmaceutics, the science of dosage form design, 2nd edition (2002) Churchill Livingstone (ISBN:0443055173).
Florence A.T. and Attwood D. Physicochemical principles of Pharmacy, 4th Edition (2006) Pharmaceutical press ISBN: 0-85369-608-X.
Walker R. and Edwards C. Clinical Pharmacy and Therapeutics, 3rd edition (2002) Churchill Livingstone.
British Pharmacopoeia 2007
In addition, students will be presented with scientific articles relevant to the above topics which they will critically appraise in workshops and self-directed study sessions |
Brief description of teaching
and learning methods:
Lectures, Workshop tutorials, Practical laboratory |
Contact hours:
| |
Autumn |
Spring |
Summer |
| Lectures |
16 |
14 |
|
| Tutorials/workshops |
4 |
6 |
|
| Practicals (including lab based activities, CAL activities
to be completed on blackboard, poster day) |
12 (4x3) |
18 (2 CAL sessions and a poster) |
|
| Private study (case study) |
15 |
15 |
|
| Preparation and analysis time for tutorials/seminars and
practicals |
32 |
48 |
|
| Directed Private Study: Reading for group presentation |
|
20 |
|
| Total hours |
79 |
121 |
|
| Number of essays or assignments |
|
1 short abstract |
|
| Other (eg major seminar paper) |
|
|
|
|
Assessment:
Coursework:
Students will attend lectures, workshops and practical classes, each containing material that is examinable at the end of the year. Attendance at practicals and workshops is compulsory.
Relative percentage of coursework: 30%
Penalties for late submission: In accordance with University policy
Examinations:
One three-hour written exam will be taken during the Part 3 examination period in the summer term (70%). Course work in the form of practical reports and case studies (30%) will also be assessed.
Requirements for a pass: a mark of 40% overall (but see progression requirements in programme specifications).
Reassessment arrangements:
Written examination during the University examination period (September) |
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